Relationship between promoter methylation and protein expression of glutathione S-transferase gene class P1 in breast cancer

Glutathione S-transferase gene class P1 (GSTP1) encodes glutathione S-transferase P1 (GSTP1) that catalyses detoxifying metabolism of glutathione. The lack of GSTP1 expression is linked to carcinogen-esis and is related to promoter methylation. The previous studies of GSTP1 hypermethylation in breast cancer reveal diverse results and suspicious...

Author : Supparit Pakdeethai BSc, Valla Fongchaiya BSc, Tanett Pongtheerat PhD., Kroon- pong Iampenkhae MD., Pichet Sampatanukul MD. MSc
Keyword : breast cancer, glutathione s-transferase, gstp1, promoter methylation
Category : Original Articles